Pathologists needed for consensus exercise

| September 1, 2009

The organizers of Endometrial Intraepithelial Neoplasia consensus exercise need more pathologists' eyes to review cases.  They want to evaluate the reliability of the diagnostic criteria for endometrial pre-cancers; Endometrial Intraepithelial Neoplasia (EIN) and ask you follow the below link and take the quiz.

Is this EIN?

Can you readily identify premalignant endometrial disease?

Adenomatous hyperplasia, Complex atypical hyperplasia or Endometrial Intraepithelial Neoplasia

Participate in an exercise to demonstrate diagnostic reproducibility

Test your diagnostic skill on cases from community practice and

See how you compare to your colleagues

Your participation is anonymous, but we ask that you

1. Only take the consensus quiz once

2. Complete the quiz (don’t just answer randomly to see the explanations)

If you would like an explanation for the answers without participating in the quiz, please contact Dr. Hecht at:

Endometrial Intraepithelial Neoplasia (EIN) is the histopathologic presentation of premalignant endometrial disease. It is not just a renaming of an old diagnostic entity, “complex hyperplasia with atypia”, but is a refined set of diagnostic criteria based on epidemiologic and genetic data.

This consensus exercise is designed to both train users to recognize precancers and to test the robustness of the subjective criteria among a broad range of users.


If you are unfamiliar with EIN diagnostic terminology and criteria, we ask that you either read this review article ( or peruse this website ( before you begin.


You will be provided with a link to the answers and a discussion when you complete the quiz, and may return to this page to see how you scored relative to other participants when the quiz closes on September 30.


We suggest that you write down all the answers before completing the form as all your responses will be lost when you prematurely close the page.

Sponsored by:

Dr. Jonathan L. Hecht – Harvard Medical School , USA Dr. Vinita Parkash – Yale University School of Medicine, USA Dr. Katharina Glatz – Universitaetsspital Basel, Switzerland

Category: Case of the Month, Conferences, Standards and Guidelines

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