January 07, 2010

Aperio Collaborates With ADCIS on Advanced Computer-Assisted Stereology Module for Digital Pathology

BY Dr. Keith J. Kaplan

Interesting news from Aperio and a partner (ADCIS) introducing stereology techniques with whole slide imaging.  The ability to visualize what is normally a 2-dimensional morphology-based slide as a 3-D structure offers possibilities for enhanced quantitation.  Sounds fascinating.

VISTA, Calif. – (Business Wire) Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, in partnership with ADCIS, (Advanced Concepts in Imaging Software) of Normandy, France, has introduced a stereology software module for the quantitative evaluation of complex 3D biological structures that originate from 2D sections, built on Aperio’s digital pathology platform.

“Aperio offers the only open digital pathology platform that supports products from third-party providers, expanding the functionality of our system and ultimately creating the broadest portfolio of digital pathology solutions on the market,” said Dirk G. Soenksen, CEO of Aperio. “The stereology module is one of many new offerings resulting from such collaborative and open relationships.”

Stereology is an effective alternative to complex image processing algorithms when structures of interest are too intricate, staining is problematic, or there is too much variability between slides or within the same slide. Stereology is used in a wide variety of applications including neuropathology, pulmonary and kidney diseases, diabetes, and cancer.

Paulette Herlin, PhD, Biologist Engineer, and her team at the Francois Baclesse Cancer Center and University of Caen, Normandy, worked closely with ADCIS to extend Aperio’s digital pathology platform to perform specific image analysis applications, including the use of stereology. “It is truly a leap forward that stereology techniques have been successfully adapted for the analysis of digital images to provide pathologists with a set of tools that compute unbiased estimations of biological parameters,” stated Dr. Herlin.

The stereology module is distributed by Aperio and is fully compatible with the company’s ImageScope™ digital slide viewing software.

Aperio currently has an installed base of more than 500 systems in 31 countries, including more than two-thirds of the top 15 rated U.S. hospitals, leading academic medical centers and reference laboratories, and 14 of the top 15 pharmaceutical companies.

About ADCIS

Founded in 1995 at the Image Processing and Analysis Research Center of Caen, France, ADCIS (Advanced Concepts in Imaging Software) develops innovative, high-performance image processing software products that are marketed worldwide through a network of specialized distributors. ADCIS also performs custom engineering work, addressing vertical market applications such as 3D structure analysis, motion analysis and security, inspection, DNA quantization, chromosome classification, and video surveillance. ADCIS’ flagship software product is Aphelion, one of the most powerful and advanced imaging software used by thousands of users worldwide to solve complex applications.

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