November 10, 2013

Is “billion-pixel” imaging possible for $200?

BY Dr. Keith J. Kaplan

Second Annual
Digital Pathology
Transforming Medicine in a Digital World
February 10-12, 2014 | San Francisco, CA

Dr. Guoan Zheng, Assistant Professor of Biomedical Engineering & Electrical Engineering at the University of Connecticut, to Present “Pushing the Resolution Limit with a Simple LED Array” at the Second Annual Digital Pathology Conference

Guoan ZhengDr. Zheng will discuss an imaging modality, termed Fourier ptychographic microscopy (FPM), which acquires multiple low-resolution images and stitches them in the Fourier domain. He will report on a FPM prototype that uses a LED array and a 2X objective lens to achieve the resolution of a 20X objective lens.

The large field of view that this system can image could be particularly useful for digital pathology, where the process of using a microscope to scan an entire sample can take dozens of minutes. With FPM, a microscope does not have to scan the different parts of a sample, as the whole sample can be imaged at once. Since the system acquires a complete set of data about the light field, it can correct errors, like out-of-focus images, so samples do not have to be rescanned.

Dr. Zheng is an assistant professor at the University of Connecticut. His research focuses on the development of new imaging technologies for biomedical applications. He received B.S. degree from Zhejiang University (China) in 2007, M.S. and Ph.D. degrees from Caltech in 2008 and 2013. He is the recipient of the Lemelson-MIT Caltech Student Prize.

Learn More   |   View Brochure   |   Share on LinkedIn   |   Register  (Save up to $400 – Register by November 15)

Save up to $1,500 with an All Access Package

Suggested All Access Package includes two short courses, Latest Advances in Molecular Pathology and Next-Generation Sequencing in Molecular Pathology: Challenges and Applications, the Genomics in Medicine symposium, plus the Digital Pathology conference track.

FINAL AGENDA

FEATURED PRESENTATION: American Telemedicine Association (ATA) Updated Guideline on Telepathology
Liron Pantanowitz, M.D., Associate Professor, Pathology, University of Pittsburgh Medical Center

FEATURED PRESENTATION: Pushing the Resolution Limit with a Simple LED Array
Guoan Zheng, Ph.D., Assistant Professor, Biomedical Engineering & Electrical Engineering, University of Connecticut

Luncheon Presentation
Ralf Huss, M.D., CMO, Definiens AG
Sponsored by:
Definiens

IN VIVO MICROSCOPY

IVM Diagnosis in Surgical Pathology: Present and Future
Maria M. Shevchuk, M.D., Anatomic Pathology & Clinical Pathology, Weill Cornell Medical College

In vivo Microscopy: Technologies, Applications and Roles for Pathologists
Guillermo J. Tearney, M.D., Ph.D., Mike & Sue Hazard Family MGH Research Scholar, Professor, Pathology, Harvard Medical School; Wellman Center for Photomedicine, Massachusetts General Hospital

In vivo Imaging of Cell and Tissue Dynamics: Towards Biologically Relevant Diagnostic Models in Surgical Pathology
Kamran Badizadegan, M.D., FCAP, Chair, Pathology & Laboratory Medicine, Nemours Children’s Hospital; Professor of Pathology, UCF College of Medicine

An Objective Image Quality Model Based on Subjective Pathology Perception Test   
Dirk Vossen, Ph.D., Director, Applications and Q&R, Philips Digital Pathology
Sponsored by:
Philips

QUANTITATIVE BIOMARKERS

The Quest for a Universal Fixative: Measuring Fixative-induced Morphologic and Antigenic Variation
Alexander “Sandy” Borowsky, M.D., Center for Comparative Medicine, University of California, Davis

New Methods for Multi-Parameter Quantitative in situ Biomarker Assessment: Nucleic Acids vs. Proteins
David L. Rimm, M.D., Ph.D., Professor, Pathology, Yale University

Mass Tags and IHC – A New Frontier for 100 Parameters and Above
Garry P. Nolan, Ph.D., Rachford and Carlota A. Harris Professor, Microbiology & Immunology, Stanford School of Medicine; Director, NHLBI Proteomics Center for Systems Immunology; Baxter Laboratory for Stem Cell Biology, Center for Clinical Science Research

Quantitative Image Analysis of Biomarkers in Breast Cancer: From Bench Side to Bed Side
Marilyn Bui, M.D., Ph.D., Director, Analytic Microscopy Core, Director, Cytopathology Fellowship Program, Associate Member & Professor, Anatomic Pathology, Sarcoma and Experimental Therapeutics, Moffitt Cancer Center; Oncological Sciences, Cell Biology, Pathology, Morsani College of Medicine, University of South Florida

MULTIPLEXING

Overview of Multiplexing and Novel Microscopy Platforms: So Many Biomarkers, So Little Tissue…
Richard Levenson, M.D., Professor and Vice Chair, Strategic Technologies, Pathology & Laboratory Medicine, University of California, Davis Medical Center

Predicting Response to Targeted Therapy in Solid Tumors Using Multivariate Indices based on Protein Biomarker Expression
Vladimir Knezevic, M.D., Senior Vice President, Research & Development, 20/20 GeneSystems, Inc.

Multiplexing in a CLIA Environment
Kenneth J. Bloom, M.D., CMO, Clarient, Inc.

IMPLEMENTATION & PRACTICE

Management of Clinical Digital Image Files
John H. Sinard, M.D., Ph.D., Professor, Pathology; Director, Pathology & Informatics; Associate Director, Anatomic Pathology, Yale University

Implementing WSI in a Large Academic Hospital
Thomas W. Bauer, M.D., Ph.D., Medical Director, ePathology, Cleveland Clinic

Image Analysis Algorithms: What Can They Do for Pathology?
Metin N. Gurcan, Ph.D., Associate Professor, Biomedical Informatics, Ohio State University

IMAGE APPLICATIONS

Use of Whole Slide Imaging for Primary Diagnosis in Canada
Andrew J. Evans, M.D., Ph.D., FRCPC, Staff Pathologist & Associate Professor, University Health Network, Laboratory Medicine Program

Digital Imaging of Peripheral Blood Smears: Challenges and Opportunities
Christopher Naugler, M.D., BScH, MSc, CCFP, FCFP, FRCPC, Assistant Professor, Pathology and Laboratory Medicine, University of Calgary, Division Head, General Pathology, Calgary Laboratory Services

Implementation of WSI for Consensus Review in Clinical Trials
Stephen M. Hewitt, M.D., Ph.D., Clinical Investigator, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute

ADVANCED IMAGING TECHNIQUES

Why Investing in Digital Imaging is a Good Bet
Anil Parwani, M.D., Ph.D., Director, Pathology Informatics, Pathology, University of Pittsburgh Medical Center

Alterations in Nanoscale Nuclear Architecture for Cancer Diagnosis and Prognosis
Yang Liu, Ph.D., Assistant Professor, Medicine, Bioengineering, Hillman Cancer Center, University of Pittsburgh

Whole Slide Image Analysis in Fine Needle Aspiration Biopsy and Cytopathology
Brian Collins, Ph.D., Associate Professor, Pathology and Immunology, Washington University, St. Louis

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