RSSCategory: Publications

Is the Pen Mightier Than the Scalpel?

| September 13, 2017 | 0 Comments

Although a surgeon’s goal is to remove cancer in its entirety during excision surgery, achieving negative margins (absence of cancer cells at the outer edge of the excised tumor specimen) can be challenging. To facilitate intraoperative diagnosis, Zhang et al. from multiple institutions in Texas developed a handheld pen-like device that rapidly identifies the molecular profile of […]

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FDA Approval of Immunotherapy For MSI-High or Mismatch Repair Deficient Tumors

| June 5, 2017 | 0 Comments

Last month the FDA approved pembrolizumab (KEYTRUDA) for adult and pediatric patients with with metastatic or unresectable, microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) solid tumors that have progressed following prior treatment. KEYTRUDA has also been approved fro MSI-H or dMMR colorectal cancers that have progressed following treatment with conventional chemotherapies. The immunooncology/immunotherapy story is fascinating. […]

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“Digital Pathology Stands to Reduce Cancer Misdiagnoses”

| May 21, 2017 | 0 Comments

With the ink dry about a month on the recent FDA approval of Philips Intellisite Pathology Solution (PIPS) for primary diagnosis, I came across this headline and others like it last week. Well known, respected pathologists and pathology informaticians at well-known cancer centers provided quotes for the articles. When you contribute to an article, you […]

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What does FDA Approval Mean for the Digital Pathology Market? Part 1

| May 15, 2017 | 0 Comments

Much is being said, written and discussed about the recent FDA clearance for Philips digital pathology solution for primary surgical pathology diagnosis. Of course, this means an advantage for Philips right now in the market as the only FDA approved whole slide imaging system for primary diagnosis. For groups and hospitals that appreciate the two main […]

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“Academic” Tweeting – Is it “Academic” and Will it Be Recognized as Such?

| March 23, 2017 | 2 Comments

Dr. Bruce Friedman over at Lab Soft News has an interesting post today on “The “Why” and “How” of Academic Tweeting”. Many of you know that Bruce is widely considered the grandfather of pathology informatics, coining the term decades ago, envisioning organizations, societies, fellowships before many. He and Mike Becich are two people I would […]

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Corista Announces Platform Integration and Collaboration with Elsevier to Deliver Enhanced Digital Pathology Workflow

| March 5, 2017 | 0 Comments

DP3 Digital Pathology Platform now offers Instant Access to Elsevier’s ExpertPathTM image library Concord, MA — Corista, a leader in integrated pathology solutions, today announced its collaboration with Elsevier, a world-leading provider of scientific, technical and medical information products and services. Corista will offer direct access to Elsevier’s ExpertPath(TM) and ImmunoQuery® from within the Pathology Dashboard(TM) of […]

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Epigenetics Changes Promote Pancreatic Cancer Metastasis

| January 20, 2017 | 0 Comments

Courtesy of Clinical OMICs – Molecular Diagnostics in Personalized Medicine Johns Hopkins researchers have published new data that suggests epigenetic changes controlling how DNA operates, provides survival advantages to a subset of pancreatic cancer cells. The results, published in the Nature Genetics article, “Epigenomic Reprogramming during Pancreatic Cancer Progression Links Anabolic Glucose Metabolism to Distant Metastasis,” […]

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Mammograms Tied to Over Diagnosis of Breast Cancer

| January 10, 2017 | 0 Comments

This kind of news seems to come up with some regular frequency – “To screen or not to screen, that is the question”. This Danish study recently reported in the Annals of Internal Medicine found that screening was not associated with a lower incidence of advanced tumors and argues that slow-growing, clinically less aggressive tumors may […]

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Prepare Submissions Now for the CAP17 Abstract Program

| December 14, 2016 | 0 Comments

Abstract and case study submissions to the College of American Pathologists (CAP) 2017 Abstract Program will be accepted beginning on Monday, January 9 through 5 p.m. Central time Friday, March 10, 2017. Accepted submissions will appear on the Archives of Pathology & Laboratory Medicine Web site as a Web-only supplement to the September 2017 issue. Awards will be presented to the winners […]

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Study Questions Value of Routine Mammograms

| October 13, 2016 | 0 Comments

A recent news brief service recently sent out highlights about a new study published in NEJM that questions the value of mammography for breast cancer screening while critics cited in the news brief call the study “deeply flawed” and suggest keeping with the recommendations. The study was conducted by researchers at Dartmouth and NCI and […]

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Doctors Significantly Better Than Google

| October 13, 2016 | 0 Comments

Every once in a while there is a headline I just shake my head at, thinking, “how did this research get funded?” This is certainly not the most startling example of this but nonetheless I think most physicians already know this could reject a null hypothesis “There is no difference between symptom apps and doctors” […]

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Telepathology at University College London Hospitals

| October 7, 2016 | 0 Comments

The Pathologist has a recent article discussing the use of telepathology for remote neuropathology cases provided from a central site with 2 other hospitals.  The article is written by Dr. Sebastian Brandner who is a Professor of Neuropathology at the University College London Institute of Neurology and Head of the Division of Neuropathology and honorary consultant neuropathologist […]

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Young Survival Coalition Expresses Concern About Overlooked Moonshot Recommedations

| September 30, 2016 | 0 Comments

I haven’t written much about the President’s Cancer Moonshot initiative recently and as much as I would like – perhaps because following some Blue Ribbon Panel recommendations and a large number of organizations and individuals expressing, in general, positive feedback among the cancer community, there hasn’t been a lot of news about next steps.  I […]

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Artificial Intelligence May Expedite Breast Cancer Risk Prediction

| September 1, 2016 | 0 Comments

Potential new technology here that may limit number of breast biopsies previously deemed “unnecessary” using artificial intelligence to aid screening with mammography with tumor protein expression. Perhaps as many as 20% of breast biopsies would be eliminated based on current figures. Key Points The software scanned patient charts, collected diagnostic features, and correlated mammogram findings […]

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