RSSCategory: Science

Register Now for CAP Webinar on HER2 Testing in Gastroesophageal Adenocarcinoma

| January 13, 2017 | 0 Comments

  In 2010, results of a phase 3 randomized controlled trial showed that targeted therapy directed against HER2 statistically significantly prolonged overall survival compared with chemotherapy alone in patients with HER2–positive advanced GEA. Because there are important differences in HER2 expression, scoring, and outcomes in GEA relative to breast carcinoma, the need for guideline recommendations […]

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OptraSCAN Selected by the National Institute of Neurological Disorders and Stroke (NINDS), NIH for Digital Pathology System for Brain Injury Studies

| January 10, 2017 | 0 Comments

OptraSCAN On-Demand Digital Pathology to Provide Robust Multiparametric Whole Slide Imaging System to the NINDS for Brain Injury Studies OptraSCAN has been chosen by the National Institute of Neurological Disorders and Stroke (NINDS), NIH to provide a high-speed, high-throughput, high-capacity, high-content digital slide scanner that is fully equipped with confocal and widefield fluorescence imaging modalities, […]

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ASCO, AMP and CAP Issue New Joint Consensus Statement to Standardize Interpretation and Reporting of Sequence Variants in Cancer

| January 3, 2017 | 0 Comments

Last month a joint consensus statement developed by ASCO, the Association for Molecular Pathology (AMP), and the College of American Pathologists (CAP) on standardizing the interpretation and reporting of sequence variants in cancer was published online ahead of the January print issue of The Journal of Molecular Diagnostics. Thank you to a loyal reader for the […]

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Mikroscan Collaborates With Johns Hopkins University School of Medicine to Develop Next-Generation Image Analysis Tools

| December 1, 2016 | 0 Comments

Research agreement creates academic collaboration to develop deep learning tools for rapid onsite evaluation of adequacy (ROSEA) December 1, 2016 Mikroscan Technologies, maker of affordable desktop real-time telemicroscopy solutions, announces a research agreement with Johns Hopkins University School of Medicine to develop automated cytology analysis tools for ROSEA. The research will be led by Johns […]

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FDA Delays Final Guidance on Regulating LDTs

| November 25, 2016 | 0 Comments

medpagetoday.com posted a brief but concise article earlier this week on the issue of FDA regulating laboratory developed tests (LDTs). While the FDA has had the ability to regulate these tests since 1976, largely once regarded as “simple and scarce” as the article mentions, not before a draft guidance issued in 2014 has the FDA […]

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Cancer Moonshot Initiative Grounded

| November 23, 2016 | 0 Comments

Previous posts on this matter referenced that even with the funding proposed in the hundreds of millions dollars (estimated $750 million proposal) a lot more would be required. I believe one critic I referenced said that even with that amount of funding, if approved, wouldn’t “get us off the ground” when it came to this […]

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Study Questions Value of Routine Mammograms

| October 13, 2016 | 0 Comments

A recent news brief service recently sent out highlights about a new study published in NEJM that questions the value of mammography for breast cancer screening while critics cited in the news brief call the study “deeply flawed” and suggest keeping with the recommendations. The study was conducted by researchers at Dartmouth and NCI and […]

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Doctors Significantly Better Than Google

| October 13, 2016 | 0 Comments

Every once in a while there is a headline I just shake my head at, thinking, “how did this research get funded?” This is certainly not the most startling example of this but nonetheless I think most physicians already know this could reject a null hypothesis “There is no difference between symptom apps and doctors” […]

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Young Survival Coalition Expresses Concern About Overlooked Moonshot Recommedations

| September 30, 2016 | 0 Comments

I haven’t written much about the President’s Cancer Moonshot initiative recently and as much as I would like – perhaps because following some Blue Ribbon Panel recommendations and a large number of organizations and individuals expressing, in general, positive feedback among the cancer community, there hasn’t been a lot of news about next steps.  I […]

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Indica Labs Advance Immuno-oncology Capabilities with Innovative Quantification of Multiplexed Chromogenic Immunohistochemistry

| September 23, 2016 | 0 Comments

Corrales, NM – Indica Labs, a leading provider of software for quantitative evaluation of digital pathology images, is pleased to announce the release of a new module for multiplex chromogenic IHC analysis using HALO™. The Multiplex IHC module can separate up to five stains simultaneously and analyze any subcellular compartment, nucleus, cytoplasm or membrane, making […]

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Case Study using HALO™ and STRATA™: Biomarkers of Anti-Tumor Immune Activity Associate with Survival in Melanoma

| September 19, 2016 | 0 Comments

Wednesday September 28th | 8 AM PDT | 11 AM EDT | 4 PM BST Presenters Dr. Tricia Cottrell, Johns Hopkins Medical School  Vlado Ovtcharov, Indica Labs PD-L1 expression in the tumor microenvironment can be both prognostic and predictive.  PD-L1 expression is often a marker of an ongoing CD8+ cytotoxic T-cell-mediated anti-tumor immune response, and thus, […]

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Artificial Intelligence May Expedite Breast Cancer Risk Prediction

| September 1, 2016 | 0 Comments

Potential new technology here that may limit number of breast biopsies previously deemed “unnecessary” using artificial intelligence to aid screening with mammography with tumor protein expression. Perhaps as many as 20% of breast biopsies would be eliminated based on current figures. Key Points The software scanned patient charts, collected diagnostic features, and correlated mammogram findings […]

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Computers Trounce Pathologists in Predicting Lung Cancer Type, Severity

| August 28, 2016 | 0 Comments

I love headlines such as these. First it was “Pigeons to Replace Pathologists in Diagnosing Benign from Malignant Tumors” now it is actual computer algorithms that get it right more times than and more so than ordinary surgical pathologists! Actually, I hope the pigeons do not get any more accurate but I do think that […]

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New Study Suggests Integrating Multiple Types of Protein Biomarkers Increases Accuracy of Early Breast Cancer Detection

| August 18, 2016 | 0 Comments

When serum protein biomarker data were used independently, clinical sensitivity and specificity for detection of breast cancer were 74.7% and 77.0%, respectively. When tumor-associated autoantibody data were used independently, clinical sensitivity and specificity for detection of breast cancer were 72.2% and 70.8%, respectively. When tumor autoantibody and serum protein data were used together, clinical sensitivity […]

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