Indica Labs Announces Second January Webinar
Indica Labs: Learn how HALO and HALO AI are advancing the study of autoimmune diseases!
Utilizing HALO Link and HALO AI to Enable a Large Autoimmune-Focused Research Network for Spatially Informed Disease Characterizations and Research
Date: 30 January 2025
Time: 8:00 – 9:00 PST | 11:00 – 12:00 EST | 16:00 – 17:00 GMT
Location: Webinar
Summary
Autoimmune diseases affect more than 23.5 million Americans, involving nearly every organ system of the human body. These diseases are characterized by chronic inflammation which leads to organ damage and can have a devastating impact on the health and quality of life of individuals living with these diseases. To better identify common pathways underlying the pathogenesis of autoimmune diseases and to define new therapies, The Accelerating Medicines Partnership® Autoimmune and Immune-Mediated Disease Program (AMP AIM), was launched to investigate Rheumatoid Arthritis (RA, Systemic Lupus Erythematosus (SLE), Psoriatic Disease (PsD), and Sjogren’s Disease (SjD) using single-cell and spatial multi-omics technologies.
To assist in this aim, the AMP AIM network has employed the HALO suite from an Amazon Web Services (AWS) environment to allow for a robust system of data sharing/viewing, histology review, and pathology scoring via HALO Link. Additionally, utilizing the tools found in HALO AI, the network can leverage novel algorithms to better define disease states and classify study participants for selection into specific projects and for advanced imaging modalities. Taken together, the HALO suite of software has enabled the AMP AIM network to better manage and understand the patient populations of this important research network.
Learning Objectives
- Introduce the AMP AIM Network
- Demonstrate how HALO Link enables image sharing and pathology scoring
- Highlight AI Algorithms that define features of the diseased tissue types
Presenter
M. Caleb Marlin PhD
Senior Scientist, Imaging Project Manager
Oklahoma Medical Research Foundation
Dr. Caleb Marlin, PhD is a Senior Staff Scientist and Imaging Project Manager in the labs of Drs. Judith James and Joel Guthridge in the Arthritis and Clinical Immunology Research Program (ACI) at the Oklahoma Medical Research Foundation (OMRF). Dr. Marlin focuses predominantly on understanding the underlying mechanisms contributing to autoimmune diseases like Lupus, Sjogren’s Disease, Rheumatoid Arthritis, and Multiple Sclerosis through Spatial Biology techniques. Alongside deep-phenotyping capabilities and single-cell technologies, in combination with ACI’s biorepository and local clinics, the James/Guthridge lab combines high-parameter imaging and multi-modal, multi-omics with clinical data to better understand these diseases and better treat patients afflicted with autoimmunity.
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SOURCE: Indica Labs
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