Memorial Sloan Kettering Cancer Center Partners with PathPresenter to Integrate New AI Module for Oncology Research
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Memorial Sloan Kettering Cancer Center (MSK) is partnering with PathPresenter, a leader in digital pathology workflow software, to integrate DeepLIIF, MSK’s new artificial intelligence (AI) algorithm, into PathPresenter’s image management platform for oncology research.
DeepLIIF is a virtual staining AI algorithm that transforms standard immunohistochemistry (IHC) images into virtual high-resolution multiplex immunofluorescence images. The module delivers automated whole-cell segmentation and precise quantification, providing oncology researchers with an accurate, efficient, reproducible, and cost-effective solution for advanced biomarker analysis.
Saad Nadeem, PhD, Assistant Attending Computer Scientist in the dual Departments of Medical Physics and Pathology, and Director of the Nadeem Lab at MSK, created DeepLIIF in collaboration with Travis J. Hollman, MD, PhD, formerly MSK’s Director of Immunomorphology Platforms and Associate Attending Pathologist. The Nadeem Lab uses advanced mathematics and machine learning to analyze multimodal and multiscale biomedical data to improve patient outcomes.
MSK deployed DeepLIIF following rigorous validation and single-site regulatory approval. During training, the algorithm demonstrated higher accuracy in whole-cell segmentation and higher sensitivity in identifying low and ultra-low IHC diaminobenzidine (DAB) expression than standard IHC. More than 150 MSK pathologists are currently using DeepLIIF within PathPresenter for digital pathology education and research.
“We are excited to partner with PathPresenter,” said Dr. Nadeem. “Integrating DeepLIIF into PathPresenter’s image management platform will allow pathologists worldwide to analyze complex pathology images more accurately and efficiently. The collaboration will also allow us to expand our offerings to include more complex oncology biomarkers in the future, such as PD-L1 and HER2.” For more information on this partnership, see here.
Dr. Nadeem’s portfolio of innovation is managed by Michael Frank, Director of Digital Health – Business Development & Licensing, in MSK’s Office of Technology, at frankm2@mskcc.org.
