RSSCategory: Reports

Register Now for CAP Webinar on HER2 Testing in Gastroesophageal Adenocarcinoma

| January 13, 2017 | 0 Comments

  In 2010, results of a phase 3 randomized controlled trial showed that targeted therapy directed against HER2 statistically significantly prolonged overall survival compared with chemotherapy alone in patients with HER2–positive advanced GEA. Because there are important differences in HER2 expression, scoring, and outcomes in GEA relative to breast carcinoma, the need for guideline recommendations […]

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Mammograms Tied to Over Diagnosis of Breast Cancer

| January 10, 2017 | 0 Comments

This kind of news seems to come up with some regular frequency – “To screen or not to screen, that is the question”. This Danish study recently reported in the Annals of Internal Medicine found that screening was not associated with a lower incidence of advanced tumors and argues that slow-growing, clinically less aggressive tumors may […]

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ASCO, AMP and CAP Issue New Joint Consensus Statement to Standardize Interpretation and Reporting of Sequence Variants in Cancer

| January 3, 2017 | 0 Comments

Last month a joint consensus statement developed by ASCO, the Association for Molecular Pathology (AMP), and the College of American Pathologists (CAP) on standardizing the interpretation and reporting of sequence variants in cancer was published online ahead of the January print issue of The Journal of Molecular Diagnostics. Thank you to a loyal reader for the […]

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Study Questions Value of Routine Mammograms

| October 13, 2016 | 0 Comments

A recent news brief service recently sent out highlights about a new study published in NEJM that questions the value of mammography for breast cancer screening while critics cited in the news brief call the study “deeply flawed” and suggest keeping with the recommendations. The study was conducted by researchers at Dartmouth and NCI and […]

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Doctors Significantly Better Than Google

| October 13, 2016 | 0 Comments

Every once in a while there is a headline I just shake my head at, thinking, “how did this research get funded?” This is certainly not the most startling example of this but nonetheless I think most physicians already know this could reject a null hypothesis “There is no difference between symptom apps and doctors” […]

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Young Survival Coalition Expresses Concern About Overlooked Moonshot Recommedations

| September 30, 2016 | 0 Comments

I haven’t written much about the President’s Cancer Moonshot initiative recently and as much as I would like – perhaps because following some Blue Ribbon Panel recommendations and a large number of organizations and individuals expressing, in general, positive feedback among the cancer community, there hasn’t been a lot of news about next steps.  I […]

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Artificial Intelligence May Expedite Breast Cancer Risk Prediction

| September 1, 2016 | 0 Comments

Potential new technology here that may limit number of breast biopsies previously deemed “unnecessary” using artificial intelligence to aid screening with mammography with tumor protein expression. Perhaps as many as 20% of breast biopsies would be eliminated based on current figures. Key Points The software scanned patient charts, collected diagnostic features, and correlated mammogram findings […]

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Computers Trounce Pathologists in Predicting Lung Cancer Type, Severity

| August 28, 2016 | 0 Comments

I love headlines such as these. First it was “Pigeons to Replace Pathologists in Diagnosing Benign from Malignant Tumors” now it is actual computer algorithms that get it right more times than and more so than ordinary surgical pathologists! Actually, I hope the pigeons do not get any more accurate but I do think that […]

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New Study Suggests Integrating Multiple Types of Protein Biomarkers Increases Accuracy of Early Breast Cancer Detection

| August 18, 2016 | 0 Comments

When serum protein biomarker data were used independently, clinical sensitivity and specificity for detection of breast cancer were 74.7% and 77.0%, respectively. When tumor-associated autoantibody data were used independently, clinical sensitivity and specificity for detection of breast cancer were 72.2% and 70.8%, respectively. When tumor autoantibody and serum protein data were used together, clinical sensitivity […]

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New Articles Published in Journal of Pathology Informatics

| August 2, 2016 | 0 Comments

Pathology informatics essentials for residents: A flexible informatics curriculum linked to accreditation council for graduate medical education milestones Walter H Henricks, Donald S Karcher, James H Harrison, John H Sinard, Michael W Riben, Philip J Boyer, Sue Plath, Arlene Thompson, Liron Pantanowitz J Pathol Inform 2016, 7:27 (6 July 2016) [ABSTRACT]   [HTML FULL TEXT]   [PDF]   […]

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Pathologists Often Disagree on Biopsy Findings

I thought we covered this more than a year ago but a recent study published in the Annals of Internal Medicine with an accompanying editorial and an article written by Troy Brown, RN on Medscape, there has been some additional dissection of the data from what is being called the “B-path (Breast Pathology) Study”. Many readers […]

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Whole Slide Imaging Safe for Kidney Biopsy Reads

| April 25, 2016 | 0 Comments

A group of authors, including several of a multi-center collaboration called Nephrotic Syndrome Study Network (NEPTUNE) recently published a concordance study looking at inter- and intraobserver concordance for interpretation of kidney biopsies. The study was recently published in Modern Pathology. Their findings highlighted in the abstract below show high concordance with standardization of reporting in kidney […]

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Faxitron Makes A Splash at USCAP

| April 7, 2016 | 0 Comments

Some time has passed since the learning and social marathon that is USCAP has concluded and more time will pass before I can do a full review of the commercial activities from the exhibit floor in Seattle. That being said, one of the companies that stands out in my mind as having a strong presence […]

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PathXL Reports Record Financial Year Results

| March 27, 2016 | 0 Comments

Results such as these and growth in users of digital pathology with software continue to highlight the digital pathology market landscape that makes a couple of points: The value proposition is about software and continues to highlight the value of what is done with a digital pathology image once a slide is digitized. A scanner […]

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