Eye-Candy: Detection of Crypt Volume and Ki67 nuclear biomarkers using Definiens XD

This is just amazing stuff. Watch Definiens XD in action first locate the nuclei; determine positive and negative Ki67 nuclei; locate the small intestine crypt; fill the crypt and “cut” the top to establish the area that can be measured.

This was a pre-clinical study done by Novartis to use both Ki67 positive nuclei as well as the area of the small intestinal crypts in a rodent model as part of their FDA submission packet. Imagine doing this manually across thousands of animal tissue samples? Ouch!

This is just a testament to how powerful Definiens is – you really can measure anything in an image.

Watch the video: